Dog
Canine Mast Cell Tumor: Signs, Grading, Surgery, and Prognosis
A complete guide to mast cell tumor (MCT) in dogs — the most common skin tumor in dogs (about 20% of all skin tumors), predisposed breeds Boxer Pug Bulldog Boston Terrier Labrador Golden, clinical signs (raised cutaneous nodule of variable appearance, "Darier sign" red flare on palpation, sometimes ulceration), pathogenesis of mast cell granules of histamine + heparin that risk anaphylaxis with careless handling, Patnaik I-II-III grading + Kiupel 2-tier high vs low, diagnosis FNA cytology + histopathology biopsy + staging, treatment surgery wide excision 2-3cm margin + adjuvant chemotherapy grade III + targeted therapy toceranib Palladia c-kit mutated, prognosis curative grade I-II vs metastatic grade III, when to see the vet, plus FAQ.